s Wong Research Group

Prof. Gerard C. L. Wong

Department of Materials Science and Engineering,
Department of Physics and
Department of Bioengineering,
University of Illinois, Urbana-Champaign,
Urbana IL 61801

We are interested in the materials science and soft condensed matter physics of biology and biomedicine. Our interests extend from fundamental science to technological applications. The group is inherently interdisciplinary; our collaborations include physicists, chemists, biologists, medical doctors, as well as materials scientists.

The group uses a wide range of experimental techniques including, quantitative, ultra-high resolution synchroton x-ray scattering and spectroscopy, x-ray and electron microscopy, massively parallel optical traps, laser-scanning confocal microscopy, and fluorescence and video-enhanced optical microscopy.

General areas of research:

We are affiliated with:

Recent News

April 2008

Abhijit Mishra won the Racheff Intel Graduate Student Research Award for his work on cell penetrating peptides.

Jan 2008

Both Lihua Yang's JACS paper from 2007 and Lori Sanders's PNAS paper from 2007 were featured on the cover of the January 2008 issue of the Materials Research Society Bulletin (see right).

Jul 2007

Ivan Smalyukh will start as an Asst. Prof. at the University of Colorado!

May 2007

Lihua Yang won the Racheff Intel Graduate Student Research Award for her work on antimicrobial peptide mimics.

older...

Last updated: May 2008 GH

Bundle of actin filaments (blue) held together electrostatically by lysozyme (orange), as obtained from molecular dynamics calculations in conjunction with synchroton x-ray diffraction experiments. These complexes can contribute to persistent airway infections in cystic fibrosis by sequestering antimicrobials. Based on these results, 'non-stick' versions of lysozyme have been made: reduction of lysozyme charge changes its geometric arrangement with actin and destabilizes the bundle, thereby recovering antimicrobial activity.